Pharmaceutical Analysis of a Novel Propargyl-linked Antifolate Antibiotic in the Mouse
John Hoody, Jeremy B. Alverson, Santosh Keshipeddy, Patrick A. Barney, Larissa Walker, Amy C. Anderson, Dennis L. Wright, Nigel D. Priestley
J. Chromatog. B 2017 1051: 54–59
Crystal Structures of Klebsiella pneumoniae Dihydrofolate Reductase Bound to Propargyl-Linked Antifolates Reveal Features for Potency and Selectivity
Kristen M. Lamb, Michael N. Lombardo, Jeremy Alverson, Nigel D. Priestley, Dennis L. Wright, Amy C. Anderson
Antimicrob. Agents Chemother. 2014 58(12) 7484–7491
Toward New Therapeutics for Skin and Soft Tissue Infections: Propargyl-Linked Antifolates Are Potent Inhibitors of MRSA and Streptococcus pyogenes
Kishore Viswanathan, Kathleen M. Frey, Eric W. Scocchera, Brooke D. Martin, P. Whitney Swain III, Jeremy B. Alverson, Nigel D. Priestley, Amy C. Anderson, Dennis L. Wright
PLoS One 2012 7(2) e29434.
Natural Product Derivatives with Bactericidal Activity Against Gram-positive Pathogens Including Methicillin-resistant Staphylococcus aureus and Vancomycin-resistant Enterococcus faecalis
Joshua B. Phillips, Adrienne E. Smith, Brian R. Kusche, Bradley A. Bessette, Jr, P. Whitney Swain, III, Stephen C. Bergmeier, Mark C. McMills, Dennis L. Wright, Nigel D. Priestley
Bioorg. Med. Chem. Lett. 2010 20(19) 5936–5938
The alternating pattern of stereochemistry in the nonactin macrocycle is required for antibacterial activity and efficient ion binding
Brian R. Kusche, Adrienne E. Smith, Michele A. McGuirl, Nigel D. Priestley
J. Am. Chem. Soc. 2009 131(47) 17155–17165
The crystal structure of Candida glabrata dihydrofolate reductase drives new inhibitor design toward efficacious antifungal agents
Jieying Liu, David B. Bolstad, Adrienne E. Smith, Nigel D. Priestley, Dennis L. Wright, Amy C. Anderson
Chem. Biol. 2008 15(9) 990–996